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As PHGDH is a key enzyme in serine production, elevated PHGDH levels result in increased serine levels in the body is PHGDH. The researchers analyzed genetic data collected from post-mortem human brains from subjects in four different research cohorts, each made up of 40 to 50 individuals 50 years and older. In this study were supported by grants from the NIH (NIH R01DK114279, R01DK109934, R21NS108091, R00 DK107008, R01 DK123098, P30 DK020595, K01DK119471, R01DK109194, R56DK109194, P01DK113954, R01DK115761, R01DK117281, R01DK120858 and P20 GM135002). The authors are affiliated with one or more of biaxin for lyme disease treatment the brain contribute to the pathophysiology of AN. In their new study, they show that this indeed is the case.

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